An original concurrent resolution setting forth the congressional budget for the United States Government for fiscal year 2007 and including the appropriate budgetary levels for fiscal years 2006 and 2008 through 2011.

Title II: Reconciliation - (Sec. 201) Requires the Committee on Energy and Natural Resources to report a reconciliation bill to the Senate, by May 16, 2006, that consists of changes within its jurisdiction sufficient to reduce budget authority and outlays by $3 billion for FY2007-FY2011.

Title III: Reserve Funds - (Sec. 301) Creates reserve funds, subject to specified conditions, for: (1) the uninsured; (2) health information technology; (3) the Asbestos Injury Trust Fund; (4) safe importation of prescription drugs; (5) reauthorization of the Secure Rural Schools and Community Self-Determination Act; (6) comprehensive immigration reform; (7) Indian claim settlement; (8) the National Flood Insurance Program; (9) protection of America's competitive edge; (10) the Land and Water Conservation Fund; (11) (deficit-neutral) chronic care case management; (12) receipts from Bonneville Power Administration; (13) extension of the enrollment period for part D (Voluntary Prescription Drug Benefit Program) of title XVIII (Medicare) of the Social Security Act (SSA); (14) negotiation of the best possible price for prescription drugs through such Program; (15) pandemic influenza preparedness planning; (16) prevention of catastrophic loss; (17) (deficit-neutral) energy legislation; (18) fire and safety programs; (19) an increase in physician payments under Medicare; (20) a Commission for Accountability and Review of Federal Agencies; and (21) a Gulf Coast Protection, Reconstruction, and Recovery Fund.

(Sec. 318) Sets forth congressional findings regarding U.S. response to global HIV/AIDS, Tuberculosis, and Malaria.

Title IV: Enforcement - (Sec. 401) Sets forth prohibitions on advance appropriations in the Senate. Excepts advance appropriations for FY2008-FY2009 for specified accounts identified for advance appropriations. Allows waiver or suspension of a point of order on advance appropriations in the Senate only by an affirmative three-fifths (60) majority vote.

(Sec. 402) States that new budget authority, outlays, and receipts resulting from designated emergency requirements (meeting specified criteria) pursuant to this resolution, in any bill, joint resolution, amendment, or conference report shall not count for certain purposes of the Congressional Budget Act of 1974, this resolution (relating to discretionary and directing spending limits in the Senate), the FY2006 budget resolution (relating to the long term direct spending), and the FY2004 budget resolution (relating to the PAYGO requirement in the Senate), until the adoption of a subsequent budget resolution. Limits such designated emergency requirements for FY2007 to $86.300 billion for the global war on terrorism and other emergencies, including U.S. border security initiatives and pandemic influenza initiatives.

(Sec. 403) Establishes specified discretionary spending limits in the Senate for FY2006-FY2009.

Makes it out of order, except in certain circumstances, to consider any legislation that would cause the discretionary spending limits in this section to be exceeded.

Permits: (1) waiver or suspension of such provisions only by an affirmative vote of three-fifths (60) of the Senate; and (2) appeals in the Senate from the decisions of the Chair on such provisions.

Requires the Chairman to adjust the discretionary spending limits, if any, set forth in the appropriate concurrent budget resolution and the committee allocations made pursuant to it in an amount provided for FY2007, if legislation is reported appropriating $6.824 billion for enhanced tax enforcement to address the "federal tax gap" for the Internal Revenue Service (IRS) and providing an additional appropriation of $500 billion for such purpose.

(Sec. 406) Requires the Chairman to notify the Senate of a Medicare funding warning that within seven years general fund contributions to Medicare funding will exceed 45% of Medicare outlays.

Makes it out of order to consider any legislation that would cause any increase in direct spending, net of proposals to change in direct spending, receipts, or revenues contained in the measure, if a Medicare Funding warning has been submitted to the Senate for two consecutive calendar years.

Permits: (1) waiver or suspension of such provisions only by an affirmative vote of three-fifths (60) of the Senate; and (2) appeals in the Senate from the decisions of the Chair on such provisions.

Requires withdrawal of the warning should legislation be enacted to reduce the general fund contribution below such percentage, as determined by the Chairman.