Iran, North Korea, and Syria Nonproliferation Reform and Modernization Act of 2011

Directs the President to establish a process to assess possible transfers to Iran of goods, services, or technology relating to nuclear, chemical, or biological weapons or ballistic missiles.

(Sec. 4) Directs the President to apply the following for at least two years against an identified person (or a controlling person, subsidiary or successor of such person): (1) arms export prohibitions, (2) Executive Order 12938 prohibitions, (3) dual use export prohibitions, (4) investment prohibitions, (5) financing prohibitions, and (6) financial assistance prohibitions.

(Sec. 5) Exempts a person from such measures if the President certifies to Congress that in the case of a transfer or acquisition of goods, services, or technology: (1) such person did not, on or after January 1, 1999, knowingly transfer to or acquire from Iran, North Korea, or Syria such goods, services, or technology; (2) such transferred goods, services, or technology did not contribute to the efforts of Iran, North Korea, or Syria to develop nuclear, biological, or chemical weapons, or ballistic or cruise missile systems, specified munitions, or destabilizing types or amounts of conventional weapons; (3) such person is subject to the primary jurisdiction of a government that is an adherent to one or more relevant nonproliferation regimes and such transfer was made in accordance with the appropriate guidelines; or (4) the government with primary jurisdiction over such person has imposed meaningful penalties on such person.

Exempts a person from such measures if the President certifies to Congress that in the case of: (1) an acquisition of materials mined or otherwise extracted within the territory of Iran, North Korea, or Syria for purposes relating to nuclear, biological, or chemical weapons, or ballistic or cruise missile development programs such person did not acquire these materials; or (2) the provision of a vessel, insurance or reinsurance, or another shipping service for the transportation of goods to or from Iran, North Korea, or Syria for purposes relating to such programs, such person did not provide a vessel or service.

(Sec. 6) Prohibits U.S. nuclear cooperation agreements and related export licenses and transfers of materials, services and goods with a country that is assisting the nuclear program of Iran, North Korea, or Syria, or is transferring advanced conventional weapons to such countries.

(Sec. 7) Directs the President to submit an annual report to Congress that identifies each country that allows foreign persons under its jurisdiction to engage in activities that are sanctionable under this Act.

(Sec. 8) Directs the President to prohibit assistance (other than humanitarian assistance) under the Foreign Assistance Act of 1961 and not issue export licenses for defense articles or defense services under the Arms Export Control Act to a foreign country that is assisting Iran, North Korea, or Syria in the acquisition, development, or proliferation of weapons of mass destruction or ballistic missiles. Authorizes the provision of such assistance if the President notifies Congress that the country is no longer assisting Iran, North Korea, or Syria in such activities.

(Sec. 9) Prohibits any U.S. government agency from making extraordinary payments in connection with the International Space Station to the Russian Aviation and Space Agency or any other organization of the government of the Russian Federation unless the President has reported to Congress that: (1) it is Russian policy to oppose the proliferation to or from Iran, North Korea, and Syria of weapons of mass destruction and missile delivery systems; (2) the government of the Russian Federation has demonstrated a commitment to prevent the transfer to or from Iran, North Korea, and Syria of goods, services, and technology that could make a material contribution to Iran's nuclear, biological, chemical weapons, or missile programs; and (3) the Russian Aviation and Space Agency has not, during the one-year period ending on the date of such presidential determination, made transfers that are reportable under this Act to or from Iran, North Korea, or Syria.

Authorizes the National Aeronautics and Space Administration (NASA) to make extraordinary payments in connection with the International Space Station to the Russian Aviation and Space Agency that would otherwise be prohibited under this Act: (1) if such payments are necessary for crew safety aboard the International Space Station; or (2) for the construction, testing, preparation, delivery, launch, or maintenance of the Service Module, and for the purchase (not to exceed $14 million) of the pressure dome for the Interim Control Module and the Androgynous Peripheral Docking Adapter for the U.S. propulsion module under specified conditions.

Directs the President to report to Congress identifying each Russian person or entity that the U.S. government has paid since November 22, 2005, for work to be performed or services to be rendered under the Agreement Concerning Cooperation on the Civil International Space Station or any related protocol, agreement, or contract.

(Sec. 10) Directs the Secretary of State to deny a visa to, and the Secretary of Homeland Security (DHS) to exclude from the United States, an alien listed in a report identifying persons involved in specified weapons proliferation activities with Iran.

(Sec. 11) Amends the Ports and Waterways Safety Act to require, before a vessel arrives at a U.S. port, the owner, charterer, operator, or master of the vessel to certify that the vessel did not enter a port in Iran, North Korea, or Syria during the 180-day period ending on the date of the vessel's U.S. port arrival.

Prohibits from landing in a U.S. port for at least two years: (1) any vessel for which a false certification was made; and (2) any other vessel owned or operated by a parent corporation, partnership, association, or individual proprietorship of the vessel for which the false certification was made.

Directs the Secretary to: (1) identify foreign ports at which vessels have landed during the preceding 12-month period that have also landed at ports in Iran, North Korea, or Syria during such period; and (2) inspect vessels arriving in the United States from such foreign ports to establish whether a vessel was involved, during the 12-month period ending on the date of the vessel's U.S. arrival, in any activity that would be sanctionable under this Act.

(Sec. 12) Directs the President to apply foreign exchange, banking, property and loan guarantee sanctions to any person who provides to or acquires from Iran, North Korea, or Syria goods or technology that is used, or is likely to be used, for military applications.

Directs the Secretary of Energy, the Secretary of Commerce, and the Nuclear Regulatory Commission (NRC), before issuing an export license for nuclear cooperation or approving a loan guarantee or any other U.S. assistance with respect to a nuclear energy project, to certify to Congress that issuing the license or approving the loan guarantee will not permit the transfer of any goods or technology that may have military application to Iran, North Korea, or Syria.

(Sec. 14) Repeals the Iran, North Korea, and Syria Nonproliferation Act.